Precision Nutrition and Metabolic Function
common.study.values.description
“Precision Nutrition and Metabolic Function”
The purposes of this study are: 1) to determine the mechanisms responsible for the development of cardiometabolic complications in some, but not all people with obesity; 2) determine the best dietary approach for cardiometabolic health; and 3) understand why some people have a stable metabolic phenotype over time whereas cardiometabolic health improves or worsens in others.
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common.study.values.methods
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Behavioral - Mediterranean diet
A Mediterranean-type diet will be consumed for 4 to 8 weeks in the weight stable state with all meals provided.
Behavioral - Low-carbohydrate, ketogenic diet
A low-carbohydrate, ketogenic diet will be consumed for 4 to 8 weeks in the weight stable state with all meals provided.
Behavioral - Low-fat diet
A low-fat diet will be consumed for 4 to 8 weeks in the weight stable state with all meals provided.
Annual follow-up testing for 5 years
Annual follow-up testing with no restrictions on dietary intake during periods between annual testing.
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Precision Nutrition and Metabolic Function
common.study.values.clinical-trial-id
NCT04131166
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egJg6d
