Mechanical Environment Pregnancy with Short Cervix
“Mechanical Environment Pregnancy With Short Cervix”
The objective of this study is to quantify the mechanical environment of pregnancies complicated by a short cervix and randomized in the Trial of Pessary in Singleton Pregnancies with a Short Cervix study with ultrasound imaging and aspiration. Aim 1: To determine the biomechanical properties of a prematurely remodeled cervix. Aim 2: To determine the impact of pessary placement on the biomechanical properties of a prematurely remodeled cervix and establish if the pessary reduces the mechanical load on the cervix through computer modeling informed by ultrasonographic measurement and cervical stiffness measurements. Aim 3: To determine if the differences in the cervical biomechanical properties after pessary placement lead to improved birth outcomes as compared to the progesterone only group.
Procedure - Ultrasound imaging
This standard of care procedure is being done for research purposes and used to collect information and measure the maternal and fetal anatomy.
Procedure - Cervical speculum examination
This standard of care procedure is being done for research purposes and used to collect tissue and measure the strength and stiffness of cervix.
Quantifying the Mechanical Environment of Pregnancy Complicated With a Short Cervix With Ultrasound Imaging and Aspiration - Ancillary Study to the Trial of Pessary in Singleton Pregnancies Trial