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Identifying Genetic Causes of Calcific Aortic Valve Disease

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Identification of Genetic Causes of Calcific Aortic Valve Disease

This study aims to identify the molecular genetic causes of the variability in development of calcific aortic valve disease in bicuspid and tricuspid aortic valves and their associated aortic dilation.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Procedure - Patients scheduled to undergo aortic valve replacement or aortic surgery at BIDMC will be approached for participation in this study.

Adult patients undergoing aortic valve replacement (AVR) and/or aortic resection will be enrolled.

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Identification of Genetic Causes of Calcific Aortic Valve Disease

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NCT04149600

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