Effects of Nicotine Salt Aerosol on Cigarette Smokers
common.study.values.description
“Effects of Nicotine Salt Aerosol on Cigarette Smokers”
This grant compares the effects of cigarette smoking, protonated nicotine ("salt") aerosol, and unprotonated nicotine aerosol on nicotine delivery, nicotine craving, and other outcomes in cigarette smokers.
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Subox Mini C with Avail 18 mg nicotine salt (protonated)
Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine salt (protonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.
Subox Mini C with Avail 18 mg nicotine (unprotonated)
Participants will be instructed to take one puff of the Subox Mini C with Avail 18 mg nicotine (unprotonated) liquid every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.
Own brand cigarette
Participants will be instructed to take one puff of a cigarette matching their typical brand every 30 seconds for 5 minutes followed by a 2nd blood draw. Next, participants will be given 90 minutes to use the product ad lib, i.e., as much as desired.
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Effects of Nicotine Salt Aerosol on Cigarette Smokers
common.study.values.clinical-trial-id
NCT03974152
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epYjQa
