Stress-Induced Scratching in Healthy and AD

Stress-induced Scratching in Healthy and AD

The purpose of this study is to examine scratching behavior and identify brain areas responsible for stress-induced spontaneous scratching in patients with atopic dermatitis (AD).

No pharmaceutical medication involved
Patients and healthy individuals accepted

Behavioral - Trier Social Stress Test (TSST)

Participants randomized to receive the acute stress condition will undergo the TSST wherein the participant will be introduced to an upcoming task (i.e., job interview) and allowed to prepare (2 minutes). The participant will then be required to speak (job interview) for 4 minutes in front of 2 experimenters. After completion of the interview, participants will be asked to perform a mental arithmetic task for 4 minutes.

Behavioral - Landscape Video

Participants randomized to receive the control condition will be watching a landscape video for 10 minutes.

The Cerebral Mechanism of Stress-Induced Spontaneous Scratching in Healthy Volunteers and Patients With Atopic Dermatitis (AD)