common.study.topics.clinical

Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet

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Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet

Evaluation of the pharmacokinetics for [14C]-benzo[a]pyrene ([14C]-BaP) and metabolites in plasma and urine over 48 hours following a 50 ng dose (5.4 nCi) alone, following 7 days' consumption of Brussels sprouts, and following 7 days' consumption of a supplement containing 3,3'-diindolylmethane (DIM).

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participant.ui.study.affiliations-map.online-study.header-virtual

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Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - [14C]-benzo[a]pyrene

Oral micro-dose (50 ng) (5.4 nCi)

Drug - Brussels sprouts before 50 ng dose

Brussels sprouts for 7 days before 50 ng (5.4 nCi) dose of BaP

Drug - DIM supplement before 50 ng dose

DIM supplement for 7 days before 50 ng (5.4 nCi) dose of BaP and coadministration with DIM supplement

participant.views.study.view.additional

participant.views.study.view.scientific-title

Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet

common.study.values.clinical-trial-id

NCT03802721

participant.views.study.view.id

erkBka