common.study.topics.clinical

Itraconazole Oral Absorption

common.study.values.description

Itraconazole Oral Absorption

For tablets to be absorbed, the drug must dissolve after being swallowed. Drugs with low solubility sometimes require the inert ingredients in tablets to help the drug dissolve after being swallowed. This study uses itraconazole as an example drug with low solubility. Itraconazole tablets with different inert ingredients and manufacturing will be administered to healthy volunteers to see if the different inert ingredients and manufacturing impact drug absorption.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - fast itraconazole tablet

100mg dose

Drug - medium itraconazole tablet

100mg dose

Drug - slow itraconazole tablet

100mg dose

Drug - oral itraconazole solution

100mg dose

participant.views.study.view.additional

participant.views.study.view.scientific-title

Prediction of Itraconazole Oral Absorption From In Vitro Dissolution

common.study.values.clinical-trial-id

NCT04035187

participant.views.study.view.id

erkr4a