common.study.topics.clinical

Endothelin Receptor Function and Acute Stress

common.study.values.description

Endothelin Receptor Function and Acute Stress

Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress. This study is an extension of the investigators previous animal work to evaluate the role of endothelin-1 during stress in humans.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Bosentan

Stress response and vascular function will be assessed 3 days following 125 mg twice per day of Bosentan

Drug - Placebo

Stress response and vascular function will be assessed 3 days following twice per day placebo

participant.views.study.view.additional

participant.views.study.view.scientific-title

Endothelin Receptor Function and Acute Stress (End-Stress)

common.study.values.clinical-trial-id

NCT02116335

participant.views.study.view.id

lej8zb