Endothelin Receptor Function and Acute Stress
common.study.values.description
“Endothelin Receptor Function and Acute Stress”
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress. This study is an extension of the investigators previous animal work to evaluate the role of endothelin-1 during stress in humans.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Bosentan
Stress response and vascular function will be assessed 3 days following 125 mg twice per day of Bosentan
Drug - Placebo
Stress response and vascular function will be assessed 3 days following twice per day placebo
participant.views.study.view.additional
participant.views.study.view.scientific-title
Endothelin Receptor Function and Acute Stress (End-Stress)
common.study.values.clinical-trial-id
NCT02116335
participant.views.study.view.id
lej8zb
