Gene Expression and Biomarker Profiling of Keloid Skin
Study Description
“Gene Expression and Biomarker Profiling of Keloid Skin”
This study aims to examine both the genetic profile and the biomarkers implicated in keloid scar formation. Hypothesis: 1. Differences in the genetic profiles of lesional and non-lesional skin contribute a given population's propensity to develop keloids 2. Differences in biomolecules expressed in subjects with and without keloids can help predict keloid occurrence and severity 3. Biomarker analysis will provide useful insights for future targeted therapies for keloid scars
Location
Methods
No pharmaceutical medication involved
Patients and healthy individuals accepted
Procedure - Biopsy and/or triamcinolone injection
Subjects will have their blood drawn during the first study visit. Subsequently, a punch biopsy and/or triamcinolone injection will be given based on group timeline.
Procedure - Excisional Biopsy
Complete excision of an earlobe keloid will be taken.
Additional Information
Official Study Title
Gene Expression and Biomarker Profiling of Keloid Skin
Clinical Trial ID
NCT03228693
ParticipAid ID
lejm5d
