common.study.topics.clinical

Gene Expression and Biomarker Profiling of Keloid Skin

common.study.values.description

Gene Expression and Biomarker Profiling of Keloid Skin

This study aims to examine both the genetic profile and the biomarkers implicated in keloid scar formation. Hypothesis: 1. Differences in the genetic profiles of lesional and non-lesional skin contribute a given population's propensity to develop keloids 2. Differences in biomolecules expressed in subjects with and without keloids can help predict keloid occurrence and severity 3. Biomarker analysis will provide useful insights for future targeted therapies for keloid scars

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Procedure - Biopsy and/or triamcinolone injection

Subjects will have their blood drawn during the first study visit. Subsequently, a punch biopsy and/or triamcinolone injection will be given based on group timeline.

Procedure - Excisional Biopsy

Complete excision of an earlobe keloid will be taken.

participant.views.study.view.additional

participant.views.study.view.scientific-title

Gene Expression and Biomarker Profiling of Keloid Skin

common.study.values.clinical-trial-id

NCT03228693

participant.views.study.view.id

lejm5d