Avapro in Obese Normotensive/Hypertensive African Americans

Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans

The purpose of this study is to test the hypothesis that hypertension increases the anti-natriuretic effects of an angiotensin receptor antagonist during mental stress in overweight/obese African-American's who retain sodium during mental stress.

Pharmaceutical medication involved
Patients and healthy individuals accepted

Drug - Irbesartan

Double blind placebo controlled cross over trial to determine effectiveness of an angiotensin receptor blocker in obese hypertensive African American patients.


Sugar pill made to look identical to irbesartan intervention.

Effectiveness of Avapro in the Treatment of Salt Sensitivity in Both Normotensive and Untreated Hypertensive Obese African Americans: A Randomized Double Blind Placebo Controlled Trial