Meal Related Interoceptive Dysfunction in Anorexia Nervosa
common.study.values.description
“Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa”
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or brain injury. By evaluating the same interoceptive sensations across different human illnesses, the investigators hope to provide convergent evidence resulting in identification of core underlying neural processes, and to discern relative contributions in each condition.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-no
Drug - Isoproterenol
Intravenous infusions of isoproterenol, delivered in a randomized double blinded order, in each participant from each group. Participants will rate the experience of heartbeat and breathing sensations as well as anxiety induced by the infusion.
Drug - Normal saline
Intravenous infusions of normal saline, delivered in a randomized double blinded order, in each participant from each group. Participants will rate the experience of heartbeat and breathing sensations as well as anxiety induced by the infusion.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
common.study.values.clinical-trial-id
NCT02615119
participant.views.study.view.id
mbkBKa
