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Metabolism and Bariatric Surgery Study

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Metabolism and Bariatric Surgery Study

The purpose of this study is to determine if diet-induced weight loss causes different changes in hormones that control appetite and glucose control than surgery-induced weight loss. The overall research plan is a non-randomized prospective study of 3 different WL interventions and a lean and an obese healthy control group.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Procedure - Roux-en-Y Gastric Bypass

NOTE: The surgery is NOT paid for by the study

Procedure - Sleeve Gastrectomy

NOTE: The surgery is NOT paid for by the study

Behavioral - Very Low Calorie Diet

Weight loss with calorie restricted liquid diet. Subjects will be placed on a 800 kcal/day diet with a meal replacement (Optifast) provided by the investigator for 12 weeks. Then, transitioning to a higher calorie diet intake up to a year. Subjects will be closely monitored by study dietitian

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Metabolic and Endocrine Effects of Bariatric Surgery

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NCT03371368

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