Mental Stress & Diesel Exhaust on Cardiovascular Health

Mental Stress & Diesel Exhaust on Cardiovascular Health

This study uses an experimental design to conduct a double-blind, randomized, crossover study where participants receive both diesel exhaust and a mental stress test in a controlled setting. My hypothesis is that the synergistic effect of stress and air pollution will result in higher levels of stress and inflammation (measured via biological markers) as well as poorer cardiovascular disease related outcomes compared to the independent effect of each exposure separately.

No pharmaceutical medication involved
Patients and healthy individuals accepted

Behavioral - Trier social stress test

Subjects are asked to give a 5 minute speech on a topic selected by the investigator. Then they are asked to subtract 7 from 758.

Diesel exhaust

Diesel exhaust is an air pollutant found in the environment and produced by cars, trucks and other transportation modes (e.g. trains, planes).

Effects of Mental Stress and Diesel Exhaust on Cardiovascular Health