Sociocultural & Biobehavioral Influences on Pain

Background: People can feel different levels of pain. This may depend on social, cultural, and biological factors. These factors can also influence how people respond to each other, and how they judge other people s experiences. Researchers want to learn more about these relationships. Objective: To study if social and cultural factors lead to differences in pain experience and how pain is interpreted by other individuals. Eligibility: Healthy adults ages 18-60 Design: Participants will have 1 or 2 visits. Participants will be screened with a medical history and nursing assessment. Participants may have the following: Electric shock through small sticky pads on the arm, leg, or foot. Thermal stimulation. A device called a thermode will be placed on the arm, leg, or foot. A computer controls the thermode temperature. Lowering their hand into very cold water. Videos or pictures of the face will recorded while participants get painful stimulation. A test to record heart electrical activity. Small metal disc or sticky pad electrodes will be placed on the chest. Pulse rate and breathing measured. Sweating will be measured with two small sensors stuck on the hand. A test to measure the electrical activity of facial muscles. Small metal disk or sticky pad electrodes will be attached to the skin. Viewing pictures and/or videos of other people who get painful and nonpainful stimulation. Participants will make decisions about the images. They will respond by keyboard, mouse, or button. Eye tracking. A camera will measure participants pupil size and follow their eye movements. ...