Prevention of Infections in Cardiac Surgery
common.study.values.description
“Prevention of Infections in Cardiac Surgery (PICS) Prevena Study”
This vanguard study will be conducted at two study sites in Canada. It is a cluster randomized trial to test a combination of two antibiotics for antibiotic prophylaxis as compared to routine prophylaxis with one single antibiotic, and to test a negative-pressure wound management system (Prevena) versus standard wound dressing to reduce chest wound infections.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-yes
common.study.methods.is-healthy-yes
Device - Prevena
Negative-Pressure Wound Management System
Drug - Cefazolin
antibiotic
Drug - Vancomycin
antibiotic
standard wound dressing
Any non-negative pressure wound dressing that is routinely used at study sites will be considered standard of care in the control arms.
participant.views.study.view.additional
participant.views.study.view.scientific-title
A Cluster-randomized Factorial Crossover Trial, Comparing Antibiotic Mono-prophylaxis With Cefazolin vs. Dual-prophylaxis With Cefazolin Plus Vancomycin and Conventional Wound Dressing vs. Prevena Negative-pressure Wound Management
common.study.values.clinical-trial-id
NCT03402945
participant.views.study.view.id
mepyXa
