“The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis”
The purpose of this study is to determine the anti-inflammatory effect of high-dose riboflavin supplementation on chronic plaque psoriasis. Psoriasis is a common chronic skin disorder that affects over 4 million people. There is no cure for psoriasis and treatment is directed at controlling patients' symptoms. Amongst patients with skin disease, there is significant interest in using complementary alternative medicine and vitamins to treat their disease. Previous human case reports suggest that riboflavin, commonly known as Vitamin B2, is clinically effective for the treatment of psoriasis; however, they were not conclusive. More recent human trials have shown that 400 mg of daily oral riboflavin is a safe and well-tolerated medication to administer to humans. For the purpose of this study, the riboflavin is used as an investigational drug.
Drug - Riboflavin
Riboflavin (Vitamin B2) 400 mg capsule taken daily for 12 weeks.
Matching placebo capsule taken daily for 12 weeks.
The Effect of Riboflavin on Moderate to Severe Plaque Type Psoriasis