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Brown Adipose Tissue Activation in Obesity

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The Effects of Capsinoids on Brown Adipose Tissue Activation in Obesity

This research study is being done to determine whether taking a dietary supplement called capsinoids, derived from sweet peppers, can activate brown fat that is already present or even generate new brown fat in individuals with excess weight. Previous studies have suggested that chronic consumption of capsinoids may be able to generate new brown fat in thin individuals. Capsinoids may also have a small positive effect on metabolism (increased calorie-burning) and fat loss. The knowledge gained in this study may eventually lead to more treatment options for people with excess weight.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Dietary Supplement - Capsinoid

Capsinoids are nunpungent analogs of capsaicin that activate BAT by stimulating sensory neurons in the gastrointestinal tract. Chronic ingestion of capsinoids may stimulate the development or recruitment of new BAT from precursor stem cells within white adipose tissue depots.

Dietary Supplement - Placebo

Placebo for capsinoid. Capsule contains no active ingredients.

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The Effects of Capsinoids on Brown Adipose Tissue Recruitment and Activation in Obesity

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NCT03110809

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vbm9rb