Field Test for Marijuana Impairment
“Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations”
Marijuana is one of the most widely used substances. This study will characterize the persistence of cannabis' (CNB's) acute effects on cognitive test performance and simulated driving over a several hour time period. The data obtained from simulated driving, cognitive tests, and biological assays of THC will be used in analyses aimed at identifying what tests or combination of tests predict both recent use and driving impairment risk. Eligible participants will undergo a full day screening visit, if still eligible they will come to Hartford Hospital in Hartford, Connecticut to take part in the full study. Participation requires overnight stays between each of the five study visits. On each of the study days participants are dosed with either a low dose of THC marijuana, a high dose of THC marijuana or placebo marijuana, (the low and high doses are repeated once each, order in which the study drug is given is double blind and chosen at random.)
Drug - Low Dose THC Marijuana
Dosing via vaporized marijuana using a lower concentration of THC, participants receive this dose on two of the five study visits.
Drug - High Dose THC Marijuana
Dosing via vaporized marijuana using a higher concentration of THC, participants receive this dose on two of the five study visits.
Drug - Placebo Marijuana
Dosing via vaporized marijuana with no THC, participants receive this dose on one of the five study visits.
Examine the Feasibility of a Standardized Field Test for Marijuana Impairment: Laboratory Evaluations