Adverse Metabolic Effects of Dietary Sugar
common.study.values.description
“Adverse Metabolic Effects of Dietary Sugar”
It is not known whether consumption of excessive amounts of sugar can increase risk factors for cardiovascular disease or diabetes in the absence of increased food (caloric) intake and weight gain, nor whether the negative effects of sugar consumption are made worse when accompanied by weight gain. This study will investigate the effects of excess sugar when consumed with an energy-balanced diet that prevents weight gain, and the effects of excess sugar when consumed with a diet that can cause weight gain. The results will determine whether excess sugar consumption and excess caloric intake that lead to weight gain have independent and additive effects on risk factors for cardiovascular disease or diabetes, and will have the potential to influence dietary guidelines and public health policy.
common.study.values.location
participant.ui.study.affiliations-map.online-study.header-virtual
participant.ui.study.affiliations-map.online-study.text
common.study.values.methods
common.study.methods.has-drugs-no
common.study.methods.is-healthy-no
high fructose corn syrup
High fructose corn syrup provided as 15% HFCS/85% water (weight/weight) fruit-flavored beverage
aspartame
Aspartame provided as 0.04% aspartame/99.96% water (weight/weight), fruit-flavored beverage
Energy-balanced diet
Provided in quantities that equal energy requirement. Formulated such that the overall macronutrient intake; including beverage; equal 45%/5% energy requirement at complex/simple carbohydrate, 35% energy requirement as fat, 15% energy requirement as protein.
Ad libitum diet
Provided in quantities that exceed energy requirement by approximately 25%. Formulated such that the overall macronutrient intake; including beverage; equals approximately 45%/5% energy requirement at complex/simple carbohydrate, 35% energy requirement as fat, 15% energy requirement as protein.
participant.views.study.view.additional
participant.views.study.view.scientific-title
Adverse Metabolic Effects of Dietary Sugar: Ad Libitum vs Energy-balanced Diets
common.study.values.clinical-trial-id
NCT02548767
participant.views.study.view.id
xbo7kb
