Treating Obsessive-Compulsive Disorder with Ketamine

Understanding How Ketamine Brings About Rapid Improvement in OCD

The purpose of this study is to understand how ketamine brings about rapid improvement in Obsessive-Compulsive Disorder (OCD) symptoms.

Pharmaceutical medication involved
Patients and healthy individuals accepted

Drug - Ketamine

OCD patients in this arm will receive 0.5mg/kg of ketamine - one single infusion

Drug - Midazolam

OCD patients in this arm will receive 0.045mg/kg of midazolam - one single infusion

NMDAR Modulation As a Therapeutic Target and Probe of Neural Dysfunction in OCD