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Immune Responses to Vaccinations in Health Subjects

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An Open Label Study of IgG Fc Glycan Composition in Human Immunity

In order to produce better more effective vaccines, it is important to understand the particulars of why individuals have an effective or ineffective immune response to vaccination. We are going to examine specific aspects of the antibody (IgG Fc glycan) made by healthy volunteers who receive different vaccines or who have a viral infection to understand the nature of an effective (or less effective) vaccine response. The results of this research could be used to develop adjuvants to increase/ improve vaccine response.

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No pharmaceutical medication involved common.study.methods.has-drugs-no
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Biological - IM Pneumococcal, meningococcal, or flu vaccine

Volunteers given one of the 3 vaccines

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An Open Label Study of IgG Fc Glycan Composition in Human Immunity

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NCT01967238

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