common.study.topics.clinical

Prevent the Onset of Rheumatoid Arthritis

common.study.values.description

Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis

The purpose of this study is to determine if hydroxychloroquine (HCQ) is safe and effective for the prevention of future onset of rheumatoid arthritis (RA) in individuals who have elevations of an autoantibody, anti-cyclic citrullinated peptide (anti-CCP3). The following recruitment strategies will be employed towards identifying healthy subjects with elevated anti-cyclic citrullinated peptide (anti-CCP3) levels: -Pre-screening: - first degree relatives of patients with rheumatoid arthritis (RA); - subjects at health-fairs; and - identification of subjects with elevated anti-CCP3 levels in the absence of inflammatory arthritis in rheumatology clinics.

common.study.values.location

participant.ui.study.affiliations-map.online-study.header-virtual

participant.ui.study.affiliations-map.online-study.text

participant.ui.study.affiliations-map.legend.locations participant.ui.study.affiliations-map.legend.selected

common.study.values.methods

Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - Hydroxychloroquine

As described. Dosing will be based upon Screening IBW.

Drug - HCQ Placebo

As described. Dosing will be based upon Screening IBW.

participant.views.study.view.additional

participant.views.study.view.scientific-title

Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis

common.study.values.clinical-trial-id

NCT02603146

participant.views.study.view.id

xe7YOb