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PET/MRI in the Diagnosis of Chronic Pain

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PET/MRI in the Diagnosis of Chronic Pain

Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain. Using [18F]-FTC-146 and positron emission tomography/magnetic resonance imaging (PET/MRI), the investigators hope to identify the source of pain generation in patients with chronic pain. The purpose of this study is to compare the uptake of [18F]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain.

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Pharmaceutical medication involved common.study.methods.has-drugs-yes
Patients and healthy individuals accepted common.study.methods.is-healthy-no

Drug - [18F]FTC-146

Adult participants will be injected with 5-10 mCi of [18F]FTC-146 and undergo a PET/MRI scan.

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Use of [18F]FTC-146 PET/MRI in the Diagnosis of Chronic Pain

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NCT03556137

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